Darius was by this time upon his march from Susa, very confident, not only in the number of his men, which amounted to six hundred thousand, but likewise in a dream, which the Persian soothsayers interpreted rather in flattery to him than according to the natural probability. He dreamed that he saw the Macedonian phalanx all on fire, and Alexander waiting on him, clad in the same dress which he himself had been used to wear when he was courier to the late king;after which, going into the temple of Belus, he vanished out of his sight. The dream would appear to have supernaturally signified to him the illustrious actions the Macedonians were to perform, and that as he, from a courier's place, had risen to the throne, so Alexander should come to be master of Asia, and not long surviving his conquests, conclude his life with glory. Darius's confidence increased the more, because Alexander spent so much time in Cilicia, which he imputed to his cowardice. But it was sickness that detained him there, which some say he contracted from his fatigues, others from bathing in the river Cydnus, whose waters were exceedingly cold. However it happened, none of his physicians would venture to give him any remedies, they thought his case so desperate, and were so afraid of the suspicions and ill-will of the Macedonians if they should fail in the cure; till Philip, the Acarnanian, seeing how critical his case was, but relying on his own well-known friendship for him, resolved to try the last efforts of his art, and rather hazard his own credit and life than suffer him to perish for want of physic, which he confidently administered to him, encouraging him to take it boldly, if he desired a speedy recovery, in order to prosecute the war. At this very time, Parmenio wrote to Alexander from the camp, bidding him have a care of Philip, as one who was bribed by Darius to kill him, with great sums of money, and a promise of his daughter in marriage. When he had perused the letter, he put it under his pillow, without showing it so much as to any of his most intimate friends, and when Philip came in with the potion, he took it with great cheerfulness and assurance, giving him meantime the letter to read. This was a spectacle well worth being present at, to see Alexander take the draught and Philip read the letter at the same time, and then turn and look upon one another, but with different sentiments; for Alexander's looks were cheerful and open, to show his kindness to and confidence in his physician, while the other was full of surprise and alarm at the accusation, appealing to the gods to witness his innocence, sometimes lifting up his hands to heaven, and then throwing himself down by the bedside, and beseeching Alexander to lay aside all fear, and follow his directions without apprehension.
For the medicine at first worked so strongly as to drive, so to say, the vital forces into the interior; he lost his speech, and falling into a swoon, had scarce any sense or pulse left. However in no long time, by Philip's means, his health and strength returned, and he showed himself in public to the Macedonians, who were in continual fear and dejection until they saw him abroad again.
There was at this time in Darius's army a Macedonian refugee, named Amyntas, one who was pretty well acquainted with Alexander's character. This man, when he saw Darius intended to fall upon the enemy in the passes and defiles, advised him earnestly to keep where he was, in the open and extensive plains, it being the advantage of a numerous army to have field-room enough when it engaged with a lesser force. Darius, instead of taking his counsel, told him he was afraid the enemy would endeavour to run away, and so Alexander would escape out of his hands. "That fear," replied Amyntas, "is needless, for assure yourself that far from avoiding you, he will make all the speed he can to meet you, and is now most likely on his march toward you." But Amyntas's counsel was to no purpose, for Darius immediately decamping, marched into Cilicia at the same time that Alexander advanced into Syria to meet him; and missing one another in the night, they both turned back again. Alexander, greatly pleased with the event, made all the haste he could to fight in the defiles, and Darius to recover his former ground, and draw his army out of so disadvantageous a place. For now he began to perceive his error in engaging himself too far in a country in which the sea, the mountains, and the river Pinarus running through the midst of it, would necessitate him to divide his forces, render his horse almost unserviceable, and only cover and support the weakness of the enemy.
Fortune was not kinder to Alexander in the choice of the ground, than he was careful to improve it to his advantage. For being much inferior in numbers, so far from allowing himself to be outflanked, he stretched his right wing much further out than the left wing of his enemies, and fighting there himself in the very foremost ranks, put the barbarians to flight. In this battle he was wounded in the thigh, Chares says, by Darius, with whom he fought hand-to-hand. But in the account which he gave Antipater of the battle, though indeed he owns he was wounded in the thigh with a sword, though not dangerously, yet he takes no notice who it was that wounded him.
Nothing was wanting to complete this victory, in which he overthrew above an hundred and ten thousand of his enemies, but the taking the person of Darius, who escaped very narrowly by flight.